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Article

Human CD8+ T cells from TB pleurisy respond to four immunodominant epitopes in Mtb CFP10 restricted by HLA-B alleles.

PloS one - 1 Jan 2013

Li Li, Yang Binyan, Yu Sifei, Zhang Xianlan, Lao Suihua, Wu Changyou

Abstract excerpt

CD8(+) T cells are essential for host defense to Mycobacterium tuberculosis (Mtb) infection and identification of CD8(+) T cell epitopes from Mtb is of importance for the development of effective peptide-based diagnostics and vaccines. We previously demonstrated that the secreted 10-KDa culture filtrate protein (CFP10) from Mtb is a potent CD8(+) T cell antigen but the repertoire and dominance pattern of human...

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Share to CD8-Positive T-Lymphocytes
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-B Antigens

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Share to Receptors, Antigen, T-Cell, alpha-beta

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Identifiers

PMID: 24349220
DOI: 10.1371/journal.pone.0082196
PMCID: PMC3861325

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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