Article
Resistance toCoccidioides immitisin Mice after Immunization with Recombinant Protein or a DNA Vaccine of a Proline-Rich Antigen
1 Jun 1999
Abstract excerpt
Two inbred strains of mice (BALB/c and C57BL/6) were vaccinated with either recombinant expression protein of a Coccidioides immitis spherule-derived proline-rich antigen (rPRA) in monophosphoryl lipid A-oil emulsion adjuvant or a DNA vaccine based on the same antigen. Four weeks after vaccination, mice were infected intraperitoneally with arthroconidia. By 2 weeks, groups of mice receiving saline or plasmids...
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