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Article

A Recombinant Aspartyl Protease of<i>Coccidioides posadasii</i>Induces Protection against Pulmonary Coccidioidomycosis in Mice

20 Dec 2005

Abstract excerpt

Coccidioidomycosis is a respiratory disease of humans caused by the desert soil-borne fungal pathogens Coccidioides spp. Recurrent epidemics of this mycosis in the southwestern United States have contributed significantly to escalated health care costs. Clinical and experimental studies indicate that prior symptomatic coccidioidomycosis induces immunity against subsequent infection, and activation of T cells is...

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PMID: 16369008
DOI: 10.1128/iai.74.1.516-527.2006

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