Article

A Recombinant Multivalent Vaccine (rCpa1) Induces Protection for C57BL/6 and HLA Transgenic Mice Against Pulmonary Infection with Both Species of Coccidioides

2021-10-21

Abstract excerpt

Coccidioidomycosis is caused by Coccidioides posadasii ( Cp ) and Coccidioides immitis ( Ci ) that have 4-5% differences in their genomic sequences. There is an urgent need to develop a human vaccine against both species. A previously created recombinant antigen (rCpa1) that contains multiple peptides derived from Cp isolate C735 is protective against the autologous isolate. The focus of this study is to eval...

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Literature Corpus work: 9bea5408-2ead-50cd-b0a4-98c6dd57bc0f
DOI: 10.1101/2021.10.20.465232

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