Article
Results of a SNP genome screen in a large Costa Rican pedigree segregating for severe bipolar disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2006
Service Susan, Molina Julio, Deyoung Joseph, Jawaheer Damini, Aldana Ileana, Vu Thuy, Araya Carmen, Araya Xinia, Bejarano Julio, Fournier Eduardo, Ramirez Magui, Mathews Carol A, Davanzo Pablo, Macaya Gabriel, Sandkuijl Lodewijk, Sabatti Chiara, Reus Victor, Freimer Nelson
Abstract excerpt
We have ascertained in the Central Valley of Costa Rica a new kindred (CR201) segregating for severe bipolar disorder (BP-I). The family was identified by tracing genealogical connections among eight persons initially independently ascertained for a genome wide association study of BP-I. For the genome screen in CR201, we trimmed the family down to 168 persons (82 of whom are genotyped), containing 25 individuals...
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