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Article

Myocyte-dependent Regulation of Endothelial Cell Syndecan-4 Expression

1 May 1999

Abstract excerpt

Syndecan-4 is a unique member of the syndecan gene family that has the ability to bind and activate protein kinase C-alpha. Whereas increased syndecan-4 levels have been noted in ischemic hearts, little is known regarding the regulation of its expression. To investigate the role of cardiac myocytes in induction of syndecan-4 expression, human endothelial cells (ECV304) were exposed to a medium conditioned by...

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PMID: 10329676
DOI: 10.1074/jbc.274.21.14786

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