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Article

Influence of endothelial cells on vascular smooth muscle cells phenotype after irradiation: implication in radiation-induced vascular damages.

The American journal of pathology - 1 Oct 2006

Milliat Fabien, François Agnès, Isoir Muriel, Deutsch Eric, Tamarat Radia, Tarlet Georges, Atfi Azeddine, Validire Pierre, Bourhis Jean, Sabourin Jean-Christophe, Benderitter Marc

Abstract excerpt

Damage to vessels is one of the most common effects of therapeutic irradiation on normal tissues. We undertook a study in patients treated with preoperative radiotherapy and demonstrated in vivo the importance of proliferation, migration, and fibrogenic phenotype of vascular smooth muscle cells (VSMCs) in radiation-induced vascular damage. These lesions may result from imbalance in the cross talk between...

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Identifiers

PMID: 17003501
DOI: 10.2353/ajpath.2006.060116
PMCID: PMC1698856

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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