Article
Influence of endothelial cells on vascular smooth muscle cells phenotype after irradiation: implication in radiation-induced vascular damages.
The American journal of pathology - 1 Oct 2006
Milliat Fabien, François Agnès, Isoir Muriel, Deutsch Eric, Tamarat Radia, Tarlet Georges, Atfi Azeddine, Validire Pierre, Bourhis Jean, Sabourin Jean-Christophe, Benderitter Marc
Abstract excerpt
Damage to vessels is one of the most common effects of therapeutic irradiation on normal tissues. We undertook a study in patients treated with preoperative radiotherapy and demonstrated in vivo the importance of proliferation, migration, and fibrogenic phenotype of vascular smooth muscle cells (...
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