Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype.

The American journal of pathology - 1 Feb 2006

Csiszar Anna, Ahmad Mansoor, Smith Kira E, Labinskyy Nazar, Gao Qun, Kaley Gabor, Edwards John G, Wolin Michael S, Ungvari Zoltan

Abstract excerpt

The transforming growth factor-beta superfamily member bone morphogenetic protein-2 (BMP-2) is up-regulated in atherosclerotic arteries; however, its effects on the endothelium are not well characterized. Using microdissected coronary arterial endothelial cells (CAECs) and cultured primary CAECs, we demonstrated endothelial mRNA expression of BMP-2 and BMP-4. The proinflammatory cytokine tumor necrosis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetylcholine
Share to Bone Morphogenetic Protein 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bone Morphogenetic Protein 4

Share to Coronary Vessels

Share to Mitogen-Activated Protein Kinase 1

Share to Mitogen-Activated Protein Kinase 3

Share to NADPH Oxidases

Share to Organ Culture Techniques

Source

Open in PubMed Open full text

Identifiers

PMID: 16436676
DOI: 10.2353/ajpath.2006.050284
PMCID: PMC1606481

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype.PMID 16436676Read ↗

Inhibition of reactive oxygen species generation attenuates TLR4-mediated proinflammatory and proliferative phenotype of vascular smooth muscle cells.Semantic proximity Read ↗

EphA2 activation promotes the endothelial cell inflammatory response: a potential role in atherosclerosis.Semantic proximity Read ↗

Bone Morphogenetic Protein-4 Promotes Phenotypic Modulation via SMAD-4/MCT-4 Axis in Vascular Smooth Muscle Cells.Semantic proximity Read ↗

Bone morphogenetic protein receptor type II deficiency and increased inflammatory cytokine production. A gateway to pulmonary arterial hypertension.Semantic proximity Read ↗

Myocyte-dependent Regulation of Endothelial Cell Syndecan-4 ExpressionSemantic proximity Read ↗

Inflammation influences vascular remodeling through AT2receptor expression and signalingSemantic proximity Read ↗

Effect of Activated Protein Kinase C Beta Type Mediated Phosphorylation of Signal Transducer and Activator of Transcription 4 on Proliferation and Phenotypic Transformation of Vascular Smooth Muscle Cells After Vascular Injury Induced by Nano-SiO₂.Semantic proximity Read ↗

Bmper inhibits endothelial expression of inflammatory adhesion molecules and protects against atherosclerosis.Semantic proximity Read ↗

Ectopic Fatty Acid-Binding Protein 4 Expression in the Vascular Endothelium is Involved in Neointima Formation After Vascular Injury.Semantic proximity Read ↗

Peroxynitrous acid-modified extracellular matrix alters gene and protein expression in human coronary artery smooth muscle cells and induces a pro-inflammatory phenotype.Semantic proximity Read ↗

Cigarette Smoke Initiates Oxidative Stress-Induced Cellular Phenotypic Modulation Leading to Cerebral Aneurysm Pathogenesis.Semantic proximity Read ↗

Bone marrow-derived macrophages exclusively expressed caveolin-2: The role of inflammatory activators and hypoxia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.