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Article

Chromosome 1p and 14q FISH Analysis in Clinicopathologic Subsets of Meningioma: Diagnostic and prognostic Implications

1 Jun 2001

Abstract excerpt

The second most frequently reported genetic abnormalities in meningiomas after 22q loss are deletions of 1p and 14q. To assess the potential diagnostic and prognostic utility of these chromosomal alterations, we studied 180 well-characterized meningiomas using dual-color fluorescence in situ hybridization (FISH) with DNA probes localized to 1p32, 1p36, 14q13, and 14q32. Our cohort consisted of 77 benign (grade...

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PMID: 11398839
DOI: 10.1093/jnen/60.6.628

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