Article
Association of polymorphisms in the beta2-adrenoreceptor gene with higher levels of parasitic infection.
Human genetics - 1 Mar 1999
Ramsay C E, Hayden C M, Tiller K J, Burton P R, Hagel I, Palenque M, Lynch N R, Goldblatt J, LeSouëf P N
Abstract excerpt
The diminishing incidence of parasitic infection in westernised societies has been suggested to result in an increased prevalance of asthma. Asthma is a polygenic disease and genome screens have shown that genes on chromosome 5q31-33 are strongly linked to the disease. The gene for the beta2-adrenoreceptor is located in this region and two polymorphisms have been identified that result in amino acid changes at...
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