Article
Fc epsilon R1-beta polymorphism and total serum IgE levels in endemically parasitized Australian aborigines.
American journal of human genetics - 1 Jul 1997
Palmer L J, Paré P D, Faux J A, Moffatt M F, Daniels S E, LeSouëf P N, Bremner P R, Mockford E, Gracey M, Spargo R, Musk A W, Cookson W O
Abstract excerpt
Endemic helminthic infection is a major public-health problem and affects a large proportion of the world's population. In Australia, helminthic infection is endemic in Aboriginal communities living in tropical northern regions of the continent. Such infection is associated with nonspecific (polyclonal) stimulation of IgE synthesis and highly elevated total serum IgE levels. There is evidence that worm-infection...
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