Article
Association of beta(2)-adrenoreceptor variants with bronchial hyperresponsiveness.
American journal of respiratory and critical care medicine - 1 Feb 2000
Ulbrecht M, Hergeth M T, Wjst M, Heinrich J, Bickeböller H, Wichmann H E, Weiss E H
Abstract excerpt
Because of its involvement in the regulation of airway tone, the beta(2)-adrenoreceptor is considered a candidate for bronchial hyperresponsiveness (BHR) associated with asthma. This notion is supported by several reports that have implicated the chromosomal region 5q31-q33 harboring the gene for the beta(2)-adrenoreceptor in the genetics of asthma and related phenotypes. We performed a population-based...
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