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Article

Analysis of murine HOXA-2 activity in Drosophila melanogaster.

Developmental genetics - 1 Jan 1999

Percival-Smith A, Bondy J A

Abstract excerpt

The murine HOXA-2 protein shares amino acid sequence similarity with Drosophila Proboscipedia (PB). In this paper, we test whether HOXA-2 and PB are functionally equivalent in Drosophila. In Drosophila, PB inhibits SCR activity required for larval T1 beard formation and adult tarsus formation and is required for maxillary palp and proboscis formation. HOXA-2 expressed from a heat-shock promoter weakly suppressed...

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PMID: 10322642
DOI: 10.1002/(SICI)1520-6408(1999)24:3/4<336::AID-DVG17>3.0.CO;2-R

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