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Article

Functional specificity of the Antennapedia homeodomain.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 1993

Furukubo-Tokunaga K, Flister S, Gehring W J

Abstract excerpt

The segmental identity in animal development is determined by a set of homeotic selector genes clustered in the invertebrate HOM or vertebrate Hox homeo box complexes. These genes encode proteins with very similar homeodomains and highly diverged N- and C-terminal sequences. The Antennapedia (Antp) homeodomain, for instance, differs at only five amino acid positions from that of Sex combs reduced (Scr) protein....

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Identifiers

PMID: 8101003
DOI: 10.1073/pnas.90.13.6360
PMCID: PMC46928

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