Functional specificity of the Antennapedia homeodomain.

doi:10.1073/pnas.90.13.6360

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Article

Functional specificity of the Antennapedia homeodomain.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 1993

Furukubo-Tokunaga K, Flister S, Gehring W J

Abstract excerpt

The segmental identity in animal development is determined by a set of homeotic selector genes clustered in the invertebrate HOM or vertebrate Hox homeo box complexes. These genes encode proteins with very similar homeodomains and highly diverged N- and C-terminal sequences. The Antennapedia (Antp) homeodomain, for instance, differs at only five amino acid positions from that of Sex combs reduced (Scr) protein....

Topics

Amino Acid Sequence
Animals
Antennapedia Homeodomain Protein
Base Sequence
DNA
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Genes, Homeobox
Homeodomain Proteins
Hot Temperature

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Nuclear Proteins

Phenotype

Recombinant Fusion Proteins

Transcription Factors

Transformation, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 8101003
DOI: 10.1073/pnas.90.13.6360
PMCID: PMC46928

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8101003-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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