Article
Structural complexity and evolutionary conservation of the Drosophila homeotic gene proboscipedia.
The EMBO journal - 1 Apr 1992
Cribbs D L, Pultz M A, Johnson D, Mazzulla M, Kaufman T C
Abstract excerpt
Mutations of the homeotic gene proboscipedia (pb) of Drosophila cause striking transformations of the adult mouthparts, to legs or antennae. We report here an analysis of the gene structure of pb. Coding sequences across a 34 kb interval yield, by alternative splicing, four identified mRNA forms which differ immediately upstream of the homeobox. As a consequence, the homeodomain is expected to reside in four...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.