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Article

Conservation of a functional hierarchy between mammalian and insect Hox/HOM genes.

The EMBO journal - 15 Apr 1994

Bachiller D, Macías A, Duboule D, Morata G

Abstract excerpt

We have generated several transgenic Drosophila strains containing different mouse Hox genes under heat shock control and studied how their generalized expression affects Drosophila larval patterns. We find that they have spatially restricted effects which correlate with their genetic order and expression pattern in the mouse; as they are expressed more posteriorly in the mouse, they have more extensive effects...

Topics

Abdomen
Animals
Animals, Genetically Modified
Biological Evolution
Drosophila
Genes, Homeobox
Head
Heat-Shock Proteins
Larva
Mice
Phenotype
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Recombinant Proteins

Suppression, Genetic

Thorax

Source

Open in PubMed Open full text

Identifiers

PMID: 7909514
DOI: 10.1002/j.1460-2075.1994.tb06462.x
PMCID: PMC395034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7909514-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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