Mouse Hox-2.2 specifies thoracic segmental identity in Drosophila embryos and larvae.

doi:10.1016/0092-8674(90)90499-5

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Article

Mouse Hox-2.2 specifies thoracic segmental identity in Drosophila embryos and larvae.

Cell - 30 Nov 1990

Malicki J, Schughart K, McGinnis W

Abstract excerpt

The mouse genome has a number of homeobox genes that are structurally similar to the Drosophila Antenapedia (Antp) gene. We find that one of the mouse Antp-like genes, Hox-2.2, when expressed in developing Drosophila cells under control of a heat shock promoter, can induce homeotic transformation...

Topics

Amino Acid Sequence
Animals
Cloning, Molecular
Drosophila
Embryo, Nonmammalian
Gene Expression
Genes, Homeobox
Heat-Shock Proteins
Larva
Mice
Molecular Sequence Data
Phenotype
Sequence Homology, Nucleic Acid
Thorax

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