Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[11 beta-hydroxysteroid-dehydrogenase: characteristics and the clinical significance of a key enzyme in cortisol metabolism].

Nederlands tijdschrift voor geneeskunde - 6 Mar 1999

Kerstens M N, Dullaart R P

Abstract excerpt

The enzyme 11 beta HSD catalyzes the interconversion of the biologically active cortisol and the biologically inactive cortisone. There are two distinct isozymes: 11 beta HSD type 1 is mainly expressed in liver and is a bidirectional enzyme, with both dehydrogenase and reductase activity. 11 beta HSD type 2 is mainly expressed in kidney and is a unidirectional enzyme with only dehydrogenase activity. 11 beta HSD...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin-Converting Enzyme Inhibitors
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hydrocortisone

Share to Hydroxysteroid Dehydrogenases

Share to Isoenzymes

Share to Kidney

Share to Receptors, Mineralocorticoid

Share to Renin-Angiotensin System

Source

Identifiers

PMID: 10321259

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[11 beta-hydroxysteroid-dehydrogenase: characteristics and the clinical significance of a key enzyme in cortisol metabolism].PMID 10321259Read ↗

[11beta-hydroxysteroide dehydrogenases. Recent advances].Semantic proximity Read ↗

11 beta-Hydroxysteroid dehydrogenase.Semantic proximity Read ↗

[Importance of the 11β-hydroxysteroid dehydrogenase enzyme in clinical disorders].Semantic proximity Read ↗

11 beta-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess.Semantic proximity Read ↗

Glucocorticoid metabolism and reproduction: a tale of two enzymesSemantic proximity Read ↗

Serum Cortisol and Cortisone as Potential Biomarkers of Partial 11β-Hydroxysteroid Dehydrogenase Type 2 Deficiency.Semantic proximity Read ↗

11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects.Semantic proximity Read ↗

11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response.Semantic proximity Read ↗

11β-Hydroxysteroid dehydrogenase type 2 in hypertension: comparison of phenotype and genotype analysis.Semantic proximity Read ↗

Human hypertension caused by mutations in the 11 beta-hydroxysteroid dehydrogenase gene: a molecular analysis of apparent mineralocorticoid excess.Semantic proximity Read ↗

[Deficiency of 11beta-hydroxysteroid dehydrogenase type 2 (syndrome of apparent mineralocorticoid excess)].Semantic proximity Read ↗

11β-Hydroxysteroid dehydrogenases and the brain: From zero to hero, a decade of progressSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.