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[11beta-hydroxysteroide dehydrogenases. Recent advances].

Annales d'endocrinologie - 1 Oct 2007

Vantyghem M-C, Marcelli-Tourvieille S, Defrance F, Wemeau J-L

Abstract excerpt

11beta-hydroxysteroide dehydrogenase (11beta-OHSD) enzymes exhibit a regulating action upon cortisol metabolism before access to its receptors. Two types of isoenzymes have been described, type 2 being the most anciently known. Type 2 11beta-OHSD, which changes cortisol into cortisone, is a unidirectional dehydrogenase mainly located in kidney, that protects mineralocorticoid receptors from illicit activation by...

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Identifiers

PMID: 17368420
DOI: 10.1016/j.ando.2007.02.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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