Article
Distinct roles of the Drosophila ninaC kinase and myosin domains revealed by systematic mutagenesis.
The Journal of cell biology - 1 Aug 1993
Porter J A, Montell C
Abstract excerpt
The Drosophila ninaC locus encodes a rhabdomere specific protein (p174) with linked protein kinase and myosin domains, required for a wild-type ERG and to prevent retinal degeneration. To investigate the role for linked kinase and myosin domains, we analyzed mutants generated by site-directed mut...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Drosophila
- Drosophila Proteins
- Electroretinography
- Eye Proteins
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Myosin Heavy Chains
- Myosins
- Phenotype
- Photoreceptor Cells
- Point Mutation
- Protein Kinases
- Temperature
- Transfection
