Article
Distinct roles of the Drosophila ninaC kinase and myosin domains revealed by systematic mutagenesis.
The Journal of cell biology - 1 Aug 1993
Porter J A, Montell C
Abstract excerpt
The Drosophila ninaC locus encodes a rhabdomere specific protein (p174) with linked protein kinase and myosin domains, required for a wild-type ERG and to prevent retinal degeneration. To investigate the role for linked kinase and myosin domains, we analyzed mutants generated by site-directed mutagenesis. Mutation of the kinase domain resulted in an ERG phenotype but no retinal degeneration. Deletion of the...
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