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Article

Association of interleukin-6 (rs1800796) but not transforming growth factor beta 1 (rs1800469) with serum calcium levels in osteoporotic patients.

Gene - 10 Sept 2018

Eftekhari Hajar, Hosseini Seyyed Reza, Pourreza Baboli Hadis, Mafi Golchin Maryam, Heidari Laleh, Abedian Zeinab, Pourbagher Roghayeh, Amjadi-Moheb Fatemeh, Mousavi Kani Seyyedeh Narges, Nooreddini Hajighorban, Akhavan-Niaki Haleh

Abstract excerpt

BACKGROUND: Osteoporosis is a multifactorial disease with a strong genetic influence. Recent studies have demonstrated that cytokines, such as TGF-β1 and interleukin 6 (IL-6) play complex roles in the normal bone metabolism and pathophysiology of osteoporosis. Here, we investigated the roles of 2 polymorphisms mapping to the promoters of TGF-β1and IL-6 genes on the genetic susceptibility to osteoporosis as well...

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Bone Density
Calcium
Case-Control Studies
Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transforming Growth Factor beta1

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PMID: 29860063
DOI: 10.1016/j.gene.2018.05.118

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