Article
Association of bone mineral density with polymorphism of the human calcium-sensing receptor locus.
Calcified tissue international - 1 Mar 2000
Tsukamoto K, Orimo H, Hosoi T, Miyao M, Ota N, Nakajima T, Yoshida H, Watanabe S, Suzuki T, Emi M
Abstract excerpt
A strong correlation between bone mass and genetic factors has been shown in twins and family studies. Some of the genes involved would regulate bone metabolism, bone formation, and resorption, all processes that determine bone mass. One candidate genes, calcium-sensing receptor (CASR) in the parathyroid gland, regulates calcium homeostasis by sensing decreases in extracellular calcium level and effecting an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
