Article
Analysis of polymorphism of the interleukin-6 gene in Thai subjects with osteoporosis.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Oct 2001
Weerakulwattana L, Tirawanchai N, Bunyaratavej N
Abstract excerpt
Osteoporosis is the imbalance between bone formation by osteoblast and bone resorption by osteoclast. The genetic factors play an important role in determining bone mass and several genes probably act as regulators of this process. Interkeukin-6 (IL-6) is one of the candidate genes to regulate bone density, since IL-6 has some effect on stimulation of osteoclast resorption and has been implicated in the...
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