Article
Liver regeneration in rats with retrorsine-induced hepatocellular injury proceeds through a novel cellular response.
The American journal of pathology - 1 Feb 2000
Gordon G J, Coleman W B, Hixson D C, Grisham J W
Abstract excerpt
The adult rodent liver contains at least two recognized populations of cells with stem-like properties that contribute to liver repair/regeneration under different pathophysiological circumstances: (i) unipotential committed progenitor cells (differentiated hepatocytes and biliary epithelial cells) and (ii) multipotential nonparenchymal progenitor cells (oval cells). In retrorsine-induced hepatocellular injury...
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