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Article

Primary isolated hepatic oval cells maintain progenitor cell phenotypes after two-year prolonged cultivation.

Journal of hepatology - 1 Nov 2010

Wang Ping, Cong Min, Liu Tian-Hui, Yang Ai-Ting, Cong Rui, Wu Peng, Tang Shu-Zhen, Xu Yong, Wang Hui, Wang Bao-En, Jia Ji-Dong, You Hong

Abstract excerpt

BACKGROUND & AIMS: Although expandable hepatic progenitors provide renewable cell sources for treatment of hepatic disorders, long-term cultivation of hepatic progenitors may affect proliferation and differentiation abilities, and even initiate the formation of malignant cancer stem cells. This study aims to determine characteristics of primary cultured hepatic oval cells after prolonged cultivation in vitro....

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Identifiers

PMID: 20739084
DOI: 10.1016/j.jhep.2010.05.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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