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Article

Plasma homocyst(e)ine concentration, but not MTHFR genotype, is associated with variation in carotid plaque area.

Stroke - 1 May 1999

Spence J D, Malinow M R, Barnett P A, Marian A J, Freeman D, Hegele R A

Abstract excerpt

BACKGROUND AND PURPOSE: Elevated plasma homocyst(e)ine [H(e)] concentration is associated with premature atherosclerosis. A common cause of elevated plasma H(e) concentration is a thermolabile mutation (677T) in the gene encoding methylenetetrahydrofolate reductase (MTHFR). We sought to determine whether plasma H(e) concentration or MTHFR genotype would be more strongly associated with carotid plaque area (CPA),...

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Source

Identifiers

PMID: 10229729
DOI: 10.1161/01.str.30.5.969

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Plasma homocyst(e)ine concentration, but not MTHFR genotype, is associated with variation in carotid plaque area.PMID 10229729Read ↗

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