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Article

Cytochrome P450 Genetic Variants and Their Metabolite Levels Associated with Plaque Stability in Patients with Ischemic Stroke.

Journal of atherosclerosis and thrombosis - 1 Jan 2016

Yi Xing-Yang, Liao Duan-Xiu, Wang Chun, Cheng Wen, Fu Xiu-Quan, Zhang Biao

Abstract excerpt

AIM: Cytochrome P450s (CYP450) enzymes regulate inflammation and atherosclerosis and can affect carotid plaque stability in patients with ischemic stroke (IS). This study aimed to investigate the association of CYP450 genetic variants with CYP plasma metabolite levels and plaque stability in patients with IS. METHODS: Eleven single nucleotide polymorphisms (SNPs) of CYP genes and their plasma metabolite...

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Identifiers

PMID: 26423716
DOI: 10.5551/jat.31120

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