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Article

Methylene tetrahydrofolate reductase genotype and the risk and extent of coronary artery disease in a population with low plasma folate.

Heart (British Cardiac Society) - 1 May 1999

Tokgözoğlu S L, Alikaşifoğlu M, Unsal, Atalar E, Aytemir K, Ozer N, Ovünç K, Usal O, Kes S, Tunçbilek E

Abstract excerpt

OBJECTIVE: To determine the effects of the thermolabile methylene tetrahydrofolate reductase (MTHFR) mutation on the presence and extent of coronary atherosclerosis in a population with low plasma folate. METHODS: 242 consecutive patients undergoing coronary angiography were prospectively evaluated for conventional risk factors, plasma homocysteine, vitamin B-12, and folate, and MTHFR genotype. The severity of...

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Identifiers

PMID: 10212171
DOI: 10.1136/hrt.81.5.518
PMCID: PMC1729026

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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