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Article

Establishment of an activated macrophage cell line, A-THP-1, and its properties.

The Tohoku journal of experimental medicine - 1 Oct 1998

Tominaga T, Suzuki M, Saeki H, Matsuno S, Tachibana T, Kudo T

Abstract excerpt

A new macrophage cell line with activated character and unique morphology was isolated by selecting adherent cells from the human monocytic cell line THP-1. The original THP-1 cells had been cultured for more than 9 years using 25 cm2 flasks, when cells with a different morphology appeared, adhering to the bottoms of the culture flasks. These were selected by discarding floating nonadherent cells at every...

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Identifiers

PMID: 10223614
DOI: 10.1620/tjem.186.99

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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