Article
Necrotic cells induce nonadherent peritoneal exudate cells to proliferate and differentiate into macrophage-like cells.
Immunological investigations - 1 Jan 2013
Yuan Xiaolin, Li Xiaohuan, Zhang Qing, Zhang Chunlei, Yang Zhen, Li Dianjun
Abstract excerpt
In a previous study, we noticed that some ascitic cells isolated from melanoma patients survive, proliferate, and differentiate into giant phagocytes after the other cells died. Similar phenomena were observed in the primary cultures of mouse lung and liver cells. In the present study, the effects of dying cells on abdominal exudate cells, and the biological characteristics of the differentiated cells were...
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