Article
Generation and characterization of U937-TR: a platform cell line for inducible gene expression in human macrophages.
Parasitology - 1 Nov 2020
Camilo Galindo Cristian, Arturo Clavijo-Ramírez Carlos
Abstract excerpt
Monocytes and macrophages are involved in a wide range of biological processes and parasitic diseases. The characterization of the molecular mechanisms governing such processes usually requires precise control of the expression of genes of interest. We implemented a tetracycline-controlled gene expression system in the U937 cell line, one of the most used in vitro models for the research of human monocytes and...
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