Article
Effect of culture conditions on the phenotype of THP-1 monocyte cell line.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Jul 2013
Aldo Paulomi B, Craveiro Vinicius, Guller Seth, Mor Gil
Abstract excerpt
PROBLEM: Macrophage function has many implications in a variety of diseases. Understanding their biology becomes imperative when trying to elucidate immune cell interactions with their environment, and in vitro cell lines allow researchers to manipulate these interactions. A common cell line used is THP-1, a promyeloid cell line suggestive to outside factors, and therefore sensitive to culture conditions. In this...
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