Article
Accumulation of glycolipids in mutant Chinese hamster ovary cells (Z65) with defective peroxisomal assembly and comparison of the metabolic rate of glycosphingolipids between Z65 cells and wild-type CHO-K1 cells.
Biochimica et biophysica acta - 19 Apr 1999
Saito M, Iwamori M, Lin B, Oka A, Fujiki Y, Shimozawa N, Kamoshita S, Yanagisawa M, Sakakihara Y
Abstract excerpt
The influence of peroxisomal dysfunction on glycosphingolipid metabolism was investigated using mutant Chinese hamster ovary (CHO) cells (Z65) with defective assembly of the peroxisomal membranes. In accordance with previous observations, the concentration of very long chain fatty acid (C24:0) was shown to be higher in Z65 cells than in control cells. We then compared the composition of glycolipids in Z65 cells...
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