Article
Myristic acid utilization in Chinese hamster ovary cells and peroxisome-deficient mutants.
The Journal of biological chemistry - 15 Sept 1992
Wang L, Yerram N R, Kaduce T L, Spector A A
Abstract excerpt
Chinese hamster ovary (CHO) cells convert [9,10-3H]myristic acid ([3H]14:0) to several lipid-soluble, radioactive metabolites that are released into the medium. The main products are lauric (12:0) and decanoic (10:0) acids. Some of the 12:0 formed also is retained in cell lipids. Similar metabolites are not synthesized from palmitic (16:0), oleic (18:1), or arachidonic (20:4) acids, and the addition of these...
Topics
- Animals
- Autoradiography
- CHO Cells
- Chromatography, High Pressure Liquid
- Cricetinae
- Electrophoresis, Polyacrylamide Gel
- Lipids
- Mass Spectrometry
- Microbodies
- Mutation
- Myristic Acid
