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Article

The role of p75NTR in modulating neurotrophin survival effects in developing motoneurons.

The European journal of neuroscience - 1 May 1999

Wiese S, Metzger F, Holtmann B, Sendtner M

Abstract excerpt

Neurotrophins exert their biological functions on neuronal cells through two types of receptors, the trk tyrosine kinases and the low-affinity neurotrophin receptor (p75NTR), which can bind all neurotrophins with similar affinity. The p75NTR is highly expressed in developing motoneurons and in adult motoneurons after axotomy, suggestive of a physiological role in mediating neurotrophin responses under such...

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Source

Identifiers

PMID: 10215920
DOI: 10.1046/j.1460-9568.1999.00585.x

Genes

NGF
BDNF
CNTF
GDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The role of p75NTR in modulating neurotrophin survival effects in developing motoneurons.PMID 10215920Read ↗

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