Article

Induction of Postnatal Schwann Cell Death by the Low-Affinity Neurotrophin ReceptorIn Vitroand after Axotomy

2000-08-01

Abstract excerpt

Schwann cells express the low-affinity neurotrophin receptor (p75), but no role for either the neurotrophins or their cognate receptors in Schwann cell development has been established. We have found that Schwann cells isolated from postnatal day 1 (P1) or P2 mice that were p75-deficient exhibited potentiated survival compared to wild-type cells after growth factor and serum withdrawal. There was, however, no disp...

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Literature Corpus work: 5bbdc346-3045-5484-a745-c5324557d077
DOI: 10.1523/jneurosci.20-15-05741.2000

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