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Article

The p75 neurotrophin receptor influences NT-3 responsiveness of sympathetic neurons in vivo.

Nature neuroscience - 1 Aug 1999

Brennan C, Rivas-Plata K, Landis S C

Abstract excerpt

To determine the role of the p75 neurotrophin receptor (p75NTR) in sympathetic neuron development, we crossed transgenic mice with mutations in p75NTR, nerve growth factor (NGF) and neurotrophin-3 (NT-3). Neuron number is normal in sympathetic ganglia of adult p75NTR-/- mice. Mice heterozygous for a NGF deletion (NGF+/-) have 50% fewer sympathetic neurons. In the absence of p75NTR (p75NTR-/- NGF+/-), however,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10412058
DOI: 10.1038/11158

Genes

NGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The p75 neurotrophin receptor influences NT-3 responsiveness of sympathetic neurons in vivo.PMID 10412058Read ↗

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