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Article

Prion protein gene polymorphisms in sheep with natural scrapie and healthy controls in Norway.

The Journal of general virology - 1 Apr 1999

Tranulis M A, Osland A, Bratberg B, Ulvund M J

Abstract excerpt

Two-hundred and forty healthy sheep and 32 cases of natural scrapie in Norway were analysed for disease-linked polymorphisms in the prion protein (PrP) gene. Scrapie was strongly associated with the presence of a valine polymorphism at codon 136 (V136), as 68.8% of the cases were homozygous (VV136) and 15.6% were valine/alanine heterozygous (VA136). All cases were homozygous arginine/arginine at codon 154...

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Identifiers

PMID: 10211978
DOI: 10.1099/0022-1317-80-4-1073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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