Article
Amino acid polymorphisms of PrP gene in Mongolian sheep.
The Journal of veterinary medical science - 1 Jan 2003
Gombojav Altangerel, Ishiguro Naotaka, Horiuchi Motohiro, Serjmyadag Dorj, Byambaa Badarch, Shinagawa Morikazu
Abstract excerpt
To characterize amino acid polymorphisms in sheep prion protein (PrP), we analyzed the PrP genes from 271 sheep of 4 breeds (Khalkh, Yeroo, Orkhon and Khangai) raised in central Mongolia (Tuv, Uvurkhangai and Selenge prefectures). A total of 16 genotypes and 8 allelic variants of the PrP gene at codons 112, 136, 154 and 171 were found. At codon 171, 1.8% of the sheep had arginine/arginine (R/R) (resistant to...
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