Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular analysis of glioma and skin-tumour alterations in a xeroderma-pigmentosum child.

International journal of cancer - 5 May 1999

Giglia G, Bouffet E, Jouvet A, Ohgaki H, Kleihues P, Sarasin A

Abstract excerpt

Xeroderma pigmentosum (XP) is a rare hereditary disease characterized by a very high frequency of skin tumours due to a defect in the nucleotide-excision-repair process. Some of these patients have also been reported to develop internal tumours with higher frequency than the normal population. Reported here are the clinical features and molecular analysis of an XP patient who developed multiple skin cancers as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to DNA Repair
Share to ErbB Receptors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, p53

Share to Glial Fibrillary Acidic Protein

Share to Glioma

Share to Skin Neoplasms

Share to Xeroderma Pigmentosum

Source

Identifiers

PMID: 10209947
DOI: 10.1002/(sici)1097-0215(19990505)81:3<345::aid-ijc6>3.0.co;2-e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Molecular analysis of glioma and skin-tumour alterations in a xeroderma-pigmentosum child.PMID 10209947Read ↗

p53 mutations in skin and internal tumors of xeroderma pigmentosum patients belonging to the complementation group C.Semantic proximity Read ↗

Association between DNA repair-deficiency and high level of p53 mutations in melanoma of Xeroderma pigmentosum.Semantic proximity Read ↗

Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients.Semantic proximity Read ↗

Complementation assays adapted for DNA repair-deficient keratinocytes.Semantic proximity Read ↗

Characteristics of UV-induced mutation spectra in human XP-D/ERCC2 gene-mutated xeroderma pigmentosum and trichothiodystrophy cells.Semantic proximity Read ↗

U.v.-hypermutability of xeroderma pigmentosum cells demonstrated with a DNA-based mutation system.Semantic proximity Read ↗

Xeroderma pigmentosum group C in a French Caucasian patient with multiple melanoma and unusual long-term survival.Semantic proximity Read ↗

High mutation frequency in ras genes of skin tumors isolated from DNA repair deficient xeroderma pigmentosum patients.Semantic proximity Read ↗

Elevated hprt mutant frequency in circulating T-lymphocytes of xeroderma pigmentosum patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.