Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Improvement of tylosin fermentation by mutation and medium optimization.

Letters in applied microbiology - 1 Feb 1999

Lee S H, Rho Y T

Abstract excerpt

A tylosin-hyperproducing mutant of Streptomyces fradiae MNU20 was isolated from 3500 strains obtained from either MNNG- or u.v.-treated S. fradiae NRRL2702. With the optimal medium, S. fradiae MNU20 was able to produce 159 mg tylosin g biomass(-1), indicating the tylosin productivity in S. fradiae NRLL2702 was increased 14-fold by mutation and medium optimization. When the effect of valine, succinate and natural...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Culture Media
Share to Fermentation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Methylnitronitrosoguanidine

Share to Streptomyces

Share to Succinic Acid

Share to Ultraviolet Rays

Share to Valine

Source

Identifiers

PMID: 10206653
DOI: 10.1046/j.1365-2672.1999.00478.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Improvement of tylosin fermentation by mutation and medium optimization.PMID 10206653Read ↗

Production of tylosin in solid-state fermentation by Streptomyces fradiae NRRL-2702 and its gamma-irradiated mutant (gamma-1).Semantic proximity Read ↗

Synthesis of hydrolytic enzymes during production of tylosin by Streptomyces fradiae.Semantic proximity Read ↗

[A study on space mutation of Streptomyces fradiae].Semantic proximity Read ↗

Characterization of mutations in regulatory genes of Tyl cluster leading to overexpression of tylosin in mutant γ-1 of Streptomyces fradiae NRRL-2702.Semantic proximity Read ↗

Production of teicoplanin by valine analogue-resistant mutant strains of Actinoplanes teichomyceticus.Semantic proximity Read ↗

[Obtaining of mutants of Streptomyces fradiae producing tylosin by action of nitrosomethylurea on synchronously germinating spores].Semantic proximity Read ↗

Branched-chain fatty acids produced by mutants of Streptomyces fradiae, putative precursors of the lactone ring of tylosin.Semantic proximity Read ↗

Enhanced lycopene content in Blakeslea trispora by effective mutation-screening method.Semantic proximity Read ↗

The use of recombinant DNA techniques to study tylosin biosynthesis and resistance in Streptomyces fradiae.Semantic proximity Read ↗

Influence of cultural conditions on lipid production by mutant strain of Rhodotorula glutinis MTCC 1151.Semantic proximity Read ↗

Strain improvement of Acremonium cellulolyticus for cellulase production by mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.