Production of tylosin in solid-state fermentation by Streptomyces fradiae NRRL-2702 and its gamma-irradiated mutant (gamma-1).

doi:10.1111/j.1472-765X.2009.02720.x

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Article

Production of tylosin in solid-state fermentation by Streptomyces fradiae NRRL-2702 and its gamma-irradiated mutant (gamma-1).

Letters in applied microbiology - 1 Nov 2009

Khaliq Shazia, Rashid Nosheen, Akhtar Kalsoom, Ghauri Muhammad Afzal

Abstract excerpt

AIMS: To develop solid-state fermentation system (SSF) for hyper production of tylosin from a mutant gamma-1 of Streptomyces fradiae NRRL-2702 and its parent strain. METHODS AND RESULTS: Various agro-industrial wastes were screened to study their effect on tylosin production in SSF. Wheat bran as solid substrate gave the highest production of 2500 microg of tylosin g(-1) substrate by mutant gamma-1 against parent...

Topics

Culture Media
Culture Techniques
Fermentation
Gamma Rays
Mutagenesis
Mutation
Streptomyces
Tylosin

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PMID: 19780953
DOI: 10.1111/j.1472-765X.2009.02720.x

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