Article
Evidence for effective suppression of recombination in the chromosome 17q21 segment spanning RNU2-BRCA1.
American journal of human genetics - 1 May 1999
Liu X, Barker D F
Abstract excerpt
Characterization of associations between polymorphic sites located throughout the approximately 200-400-kb variable-length region spanning RNU2-BRCA1 reveals nearly complete linkage disequilibrium. This segment spans the RNU2 array, which includes 6-30 tandem copies of the U2 snRNA gene, and an adjacent region containing NBR1, the LBRCA1 pseudogene, NBR2, and BRCA1 in a tandemly duplicated structure. A series of...
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