Article
Long-range sequence composition mirrors linkage disequilibrium pattern in a 1.13 Mb region of human chromosome 22.
Human molecular genetics - 15 Nov 2001
Eisenbarth I, Striebel A M, Moschgath E, Vogel W, Assum G
Abstract excerpt
Association studies, the most powerful tool for the identification of genes underlying complex traits, depend on the observation of linkage disequilibrium (LD) between marker alleles and the trait. The LD pattern of the human genome which determines the regional density of required markers is non-uniform, with regions of long-range LD over several hundred kilobases and regions where LD extends only over a few...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
