Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Direct visualization of the highly polymorphic RNU2 locus in proximity to the BRCA1 gene.

PloS one - 1 Jan 2013

Tessereau Chloé, Buisson Monique, Monnet Nastasia, Imbert Marine, Barjhoux Laure, Schluth-Bolard Caroline, Sanlaville Damien, Conseiller Emmanuel, Ceppi Maurizio, Sinilnikova Olga M, Mazoyer Sylvie

Abstract excerpt

Although the breast cancer susceptibility gene BRCA1 is one of the most extensively characterized genetic loci, much less is known about its upstream variable number tandem repeat element, the RNU2 locus. RNU2 encodes the U2 small nuclear RNA, an essential splicing element, but this locus is missing from the human genome assembly due to the inherent difficulty in the assembly of repetitive sequences. To fill the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Neoplasms
Share to Chromosomes, Human, Pair 17

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA1

Share to Genetic Loci

Share to In Situ Hybridization, Fluorescence

Share to Microsatellite Repeats

Share to Physical Chromosome Mapping

Share to RNA, Small Nuclear

Source

Open in PubMed Open full text

Identifiers

PMID: 24146815
DOI: 10.1371/journal.pone.0076054
PMCID: PMC3795722

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Direct visualization of the highly polymorphic RNU2 locus in proximity to the BRCA1 gene.PMID 24146815Read ↗

Estimation of the RNU2 macrosatellite mutation rate by BRCA1 mutation tracing.Semantic proximity Read ↗

A human supergene: <i>BRCA1, CCDC200</i> , and U2 snRNAsSemantic proximity Read ↗

Evidence for effective suppression of recombination in the chromosome 17q21 segment spanning RNU2-BRCA1.Semantic proximity Read ↗

The 22q11 low copy repeats are characterized by unprecedented size and structure variabilitySemantic proximity Read ↗

Assignment of the human BC200 RNA gene (BCYRN1) to chromosome 2p16 by radiation hybrid mapping.Semantic proximity Read ↗

Genome scanning by two-dimensional DNA typing: the use of repetitive DNA sequences for rapid mapping of genetic traits.Semantic proximity Read ↗

Expansion of a 12-kb VNTR containing the REXO1L1 gene cluster underlies the microscopically visible euchromatic variant of 8q21.2.Semantic proximity Read ↗

Significant contribution of germline BRCA2 rearrangements in male breast cancer families.Semantic proximity Read ↗

Detection of an insertion deletion of region 8q13-q21.2 in a patient with Duane syndrome: implications for mapping and cloning a Duane gene.Semantic proximity Read ↗

Localization of new, microdissection- generated, anonymous markers and of the genes Pcsk1, Dhfr, Ndub13, and Ccnb1 to rat chromosome region 2q1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.