Article
Three different MHC class I molecules bind the same CTL epitope of the influenza virus in a primate species with limited MHC class I diversity.
Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 1999
Evans D T, Knapp L A, Jing P, Piekarczyk M S, Hinshaw V S, Watkins D I
Abstract excerpt
One of the most remarkable features of the MHC class I loci of most outbred mammalian populations is their exceptional diversity, yet the functional importance of this diversity remains to be fully understood. The cotton-top tamarin (Saguinus oedipus) is unusual in having MHC class I loci that exhibit both limited polymorphism and sequence variation. To investigate the functional implications of limited MHC class...
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