Article
Two different primate species express an identical functional MHC class I allele.
Immunogenetics - 1 Jan 1998
Evans D T, Piekarczyk M S, Cadavid L, Hinshaw V S, Watkins D I
Abstract excerpt
The products of the highly polymorphic and variable major histocompatibility complex (MHC) class I loci play a crucial role in host defenses against infectious disease. While similar alleles have been found in closely related species, sharing of a functional MHC class I allele between two species has never been reported. Here we show that an identical functional MHC class I molecule is present in two different...
Topics
- Alleles
- Animals
- Base Sequence
- Biological Evolution
- DNA, Complementary
- Genes, MHC Class I
- Influenza A virus
- Molecular Sequence Data
- Nucleocapsid Proteins
- Nucleoproteins
- Saguinus