Article
Unusually high frequency MHC class I alleles in Mauritian origin cynomolgus macaques.
Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 2005
Krebs Kendall C, Jin ZheYuan, Rudersdorf Richard, Hughes Austin L, O'Connor David H
Abstract excerpt
Acute shortages of Indian origin Rhesus macaques significantly hinder HIV/AIDS research. Cellular immune responses are particularly difficult to study because only a subset of animals possess MHC class I (MHC I) alleles with defined peptide-binding specificities. To expand the pool of nonhuman primates suitable for studies of cellular immunity, we defined 66 MHC I alleles in Cynomolgus macaques (Macaca...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
