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Article

CHD1 interacts with SSRP1 and depends on both its chromodomain and its ATPase/helicase-like domain for proper association with chromatin.

Chromosoma - 1 Apr 1999

Kelley D E, Stokes D G, Perry R P

Abstract excerpt

CHD1, an Mr approximately 200,000 protein that contains a chromodomain (C), an ATPase/helicase-like domain (H) and a DNA-binding domain (D), was previously shown to be associated with decompacted interphase chromatin in mammalian cells and with transcriptionally active puffs and interbands in Drosophila polytene chromosomes. We now show by transient transfection experiments with genes expressing wild-type and...

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Source

Identifiers

PMID: 10199952
DOI: 10.1007/s004120050347

Genes

CHD1
SSRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CHD1 interacts with SSRP1 and depends on both its chromodomain and its ATPase/helicase-like domain for proper association with chromatin.PMID 10199952Read ↗

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Investigations of CHD1 function in transcription and development of Drosophila melanogaster.Semantic proximity Read ↗

The chromodomains of CHD1 are critical for enzymatic activity but less important for chromatin localization.Semantic proximity Read ↗

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