Article
The chromodomains of CHD1 are critical for enzymatic activity but less important for chromatin localization.
Nucleic acids research - 1 Apr 2011
Morettini Stefano, Tribus Martin, Zeilner Anette, Sebald Johanna, Campo-Fernandez Beatriz, Scheran Gabriele, Wörle Hildegard, Podhraski Valerie, Fyodorov Dmitry V, Lusser Alexandra
Abstract excerpt
The molecular motor protein CHD1 has been implicated in the regulation of transcription and in the transcription-independent genome-wide incorporation of H3.3 into paternal chromatin in Drosophila melanogaster. A key feature of CHD1 is the presence of two chromodomains, which can bind to histone...
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